Detailed Report Overview
What is on The Perthera Report
How do you read it?
There are seven easy-to-read sections in the Perthera Report
Section 1: Summary
A summary of relevant previous cancer treatments and comorbidities distilled from the patient’s medical records.
Section 2: Multi-Omic Results
A summary of relevant molecular findings distilled from your laboratory tests, including DNA and protein alterations.
Section 3: Summary Recommendations
The suggested guidance of the experts from the molecular tumor board after analyzing the patient’s case.
Section 4: Ranked Therapy
A list of possible monotherapies and drug combinations, prioritized according to their ability to target the patients specific cancer biomarkers. This information is integrated into a scoring model that combines the patient’s personal history, test results, location, and expert discussion, with the aid of AI and input from the Virtual Molecular Tumor Board.
Score: The therapy’s rank is driven by the patient’s total score and is color coded to indicate if treatment is a standard option, clinical trial or expanded access.
Perthera Scoring Model: The report uses three categories of scoring which are combined to make the total score: Molecular, Disease and Patient. Scores are calculated as follows:
Molecular
(0-3 Score)
Using Biomarker Profile
0
Neutrally predictive
1
Weakly predictive
2
Moderately predictive
3
Strongly predictive
Disease
(0-4 Score)
0
Unsupportive evidence or clinical activity
1
Limited clinical evidence activity
2
Emerging evidence or modest activity
3
Promising evidence or moderate activity
4
Strong clinical evidence or activity
Patient
(0-2 Score)
0
Re-challenge is a major concern
1
Re-challenge is a minor concern
2
Treatment history is not a concern